GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gsk3b | affects phosphorylation | EXP | | 6480464 | CTD | Okadaic Acid affects the phosphorylation of GSK3B protein | PMID:27050422 | Gsk3b | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]]; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]; Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein] | PMID:27050422 | Gsk3b | increases expression | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | Okadaic Acid results in increased expression of GSK3B protein; Okadaic Acid results in increased expression of GSK3B protein modified form | PMID:21715663 | Gsk3b | increases phosphorylation | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | Okadaic Acid results in increased phosphorylation of GSK3B protein | PMID:26836014 | Gsk3b | multiple interactions | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Okadaic Acid; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; Okadaic Acid inhibits the reaction [resveratrol results in decreased phosphorylation of GSK3B protein] | PMID:21715663 PMID:23292070 | | ||||||||||||||||||||||
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