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GENE - TERM ANNOTATION REPORT

RGD ID: 733880
Species: Homo sapiens
RGD Object: Gene
Symbol: CDK12
Name: cyclin dependent kinase 12
Acc ID: GO:0008353
Term: RNA polymerase II CTD heptapeptide repeat kinase activity
Definition: Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + phosphorylated RNA polymerase II.
Definition Source(s): EC:2.7.11.23, GOC:mah, PMID:28248323
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDK12enablesIBAFB:FBgn0037093 or PANTHER:PTN001936021 or PomBase:SPAC2F3.15 or UniProtKB:Q14004 or UniProtKB:Q9NYV4150520179GO_Central GO_REF:0000033
CDK12enablesIDA 150520179GO_Central PMID:22988298

PMID:22988298
CDK12enablesIEARHEA:10216150520179RHEA GO_REF:0000116
CDK12enablesIEAPANTHER:PTHR24056:SF126150520179TreeGrafter GO_REF:0000118
CDK12enablesIEAEC:2.7.11.23150520179UniProt GO_REF:0000003
CDK12enablesIMP 150520179UniProt PMID:20952539

PMID:20952539
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