GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Wnt4 | decreases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of WNT4 mRNA | PMID:19770486 PMID:21715664 PMID:21803694 PMID:27195522 | Wnt4 | multiple interactions | EXP | | 6480464 | CTD | Benzo(a)pyrene promotes the reaction [AHR protein binds to WNT4 promoter] | PMID:19654925 | Wnt4 | decreases methylation | ISO | WNT4 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of WNT4 promoter | PMID:27901495 | Wnt4 | increases expression | ISO | WNT4 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of WNT4 mRNA | PMID:32234424 | |
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