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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733710
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC22A5
Name: solute carrier family 22 member 5
Acc ID: CHEBI:17456
Term: dithioerythritol
Definition: The meso-diastereomer of 1,4-dimercaptobutane-2,3-diol; a sulfur-containing sugar derived from the monosaccharide erythrose; and an epimer of dithiothreitol.
Chemical ID: MESH:D004226
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC22A5multiple interactionsISOSlc22a5 (Rattus norvegicus)6480464CTDDithioerythritol inhibits the reaction [Mercuric Chloride results in decreased transport of SLC22A5 protein]; Dithioerythritol inhibits the reaction [Methylmercury Compounds results in decreased transport of SLC22A5 protein]; Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]PMID:19041296 PMID:22900493
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