Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733701
Species: Mus musculus
RGD Object: Gene
Symbol: Epb41l1
Name: erythrocyte membrane protein band 4.1 like 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epb41l1multiple interactionsEXP 6480464CTDAHR protein affects the reaction [Benzo(a)pyrene affects the expression of EPB41L1 mRNA]PMID:22228805
Epb41l1affects methylationISOEPB41L1 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of EPB41L1 3' UTRPMID:27901495
Epb41l1decreases expressionISOEPB41L1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of EPB41L1 mRNAPMID:20064835
Epb41l1increases expressionISOEPB41L1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of EPB41L1 mRNA; Benzo(a)pyrene results in increased expression of EPB41L1 proteinPMID:20106945 PMID:21632981 PMID:22316170 PMID:32234424 PMID:32717239
Epb41l1increases methylationISOEPB41L1 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of EPB41L1 5' UTR; Benzo(a)pyrene results in increased methylation of EPB41L1 exonPMID:27901495
Go Back to source page   Continue to Ontology report