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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733673
Species: Mus musculus
RGD Object: Gene
Symbol: Hadhb
Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hadhbincreases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of HADHB mRNAPMID:17681415 PMID:18467677 PMID:19429403 PMID:20936131 PMID:30711707
Hadhbmultiple interactionsEXP 6480464CTDPPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of HADHB mRNA]PMID:18467677 PMID:20936131
Hadhbincreases expressionISOHadhb (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in increased expression of HADHB mRNA; perfluorooctanoic acid results in increased expression of HADHB proteinPMID:16221955 PMID:19162173 PMID:22071372 PMID:34958885
Hadhbincreases expressionISOHADHB (Homo sapiens)6480464CTDperfluorooctanoic acid results in increased expression of HADHB mRNAPMID:32588087
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