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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733571
Species: Homo sapiens
RGD Object: Gene
Symbol: NLGN3
Name: neuroligin 3
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NLGN3decreases expressionEXP 6480464CTDHydrogen Peroxide results in decreased expression of NLGN3 mRNAPMID:27624276
NLGN3increases methylationEXP 6480464CTDHydrogen Peroxide results in increased methylation of NLGN3 promoterPMID:27624276
NLGN3multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NLGN3 promoter]; Glutathione inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased methylation of NLGN3 promoter]; S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA]; S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NLGN3 promoter]PMID:27624276
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