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GENE - TERM ANNOTATION REPORT

RGD ID: 733487
Species: Mus musculus
RGD Object: Gene
Symbol: Ccr5
Name: C-C motif chemokine receptor 5
Acc ID: DOID:13406
Term: pulmonary sarcoidosis
Definition: A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction. (DO)
Definition Source(s): https://www.atsjournals.org/doi/full/10.1164/rccm.201006-0865CI "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccr5 ISOCCR5 (Homo sapiens)4892066RGDDNA:polymorphisms:5' utr:multiple (human) 
Ccr5disease_progressionISOCCR5 (Homo sapiens)4892099RGDprotein:altered expression:lung, lymphocyte, macrophage (human) 
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