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GENE - TERM ANNOTATION REPORT

RGD ID: 733483
Species: Homo sapiens
RGD Object: Gene
Symbol: MTHFR
Name: methylenetetrahydrofolate reductase
Acc ID: DOID:1936
Term: atherosclerosis
Definition: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. (DO)
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MTHFRseverityIAGP 6893579RGDassociated with Kidney Failure, Chronic; DNA:transversion:cds:g.1298A>C (human) 
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