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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733473
Species: Homo sapiens
RGD Object: Gene
Symbol: IRS1
Name: insulin receptor substrate 1
Acc ID: CHEBI:28819
Term: naringin
Definition: A disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Chemical ID: MESH:C005274
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IRS1multiple interactionsISOIrs1 (Mus musculus)6480464CTDnaringin inhibits the reaction [Dietary Fats results in decreased phosphorylation of IRS1 protein]PMID:22198281
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