GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TGFBR1 | increases expression | ISO | Tgfbr1 (Rattus norvegicus) | 6480464 | CTD | Thioacetamide results in increased expression of TGFBR1 mRNA | PMID:28181416 PMID:34492290 | TGFBR1 | increases response to substance | ISO | Tgfbr1 (Mus musculus) | 6480464 | CTD | TGFBR1 protein results in increased susceptibility to Thioacetamide | PMID:28560358 | TGFBR1 | multiple interactions | ISO | Tgfbr1 (Rattus norvegicus) | 6480464 | CTD | [Thioacetamide co-treated with Cyclosporine] results in increased expression of TGFBR1 protein; [Thioacetamide co-treated with Lipopolysaccharides] results in increased expression of TGFBR1 mRNA | PMID:15770714 PMID:17621560 | TGFBR1 | multiple interactions | ISO | Tgfbr1 (Mus musculus) | 6480464 | CTD | [TGFBR1 protein results in increased susceptibility to Thioacetamide] which results in increased cleavage of CASP3 protein; [TGFBR1 protein results in increased susceptibility to Thioacetamide] which results in increased expression of GPT protein; TGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of CCN2 mRNA]; TGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of PDGFA mRNA]; TGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of PDGFB mRNA]; TGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of TGFB1 mRNA] | PMID:28560358 | |
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