GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NR1H3 | decreases expression | ISO | Nr1h3 (Rattus norvegicus) | 6480464 | CTD | Diethylhexyl Phthalate results in decreased expression of NR1H3 mRNA; Diethylhexyl Phthalate results in decreased expression of NR1H3 protein | PMID:34438493 | NR1H3 | increases expression | ISO | Nr1h3 (Mus musculus) | 6480464 | CTD | Diethylhexyl Phthalate results in increased expression of NR1H3 mRNA | PMID:25949234 | NR1H3 | multiple interactions | ISO | Nr1h3 (Mus musculus) | 6480464 | CTD | [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of NR1H3 protein; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with Dietary Fats] results in increased expression of NR1H3 mRNA | PMID:23756648 PMID:25270622 | | ||||||||||||||||||||||
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