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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733329
Species: Homo sapiens
RGD Object: Gene
Symbol: ENTPD1
Name: ectonucleoside triphosphate diphosphohydrolase 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ENTPD1increases expressionEXP 6480464CTDOxygen deficiency results in increased expression of ENTPD1 mRNA; Oxygen deficiency results in increased expression of ENTPD1 proteinPMID:27899277
ENTPD1multiple interactionsEXP 6480464CTD17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Oxygen deficiency results in increased expression of ENTPD1 protein]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ENTPD1 protein]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of ENTPD1 protein]PMID:27899277
ENTPD1increases expressionISOEntpd1 (Mus musculus)6480464CTDOxygen deficiency results in increased expression of ENTPD1 mRNA; Oxygen deficiency results in increased expression of ENTPD1 proteinPMID:23437309
ENTPD1multiple interactionsISOEntpd1 (Mus musculus)6480464CTD[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ENTPD1 mRNAPMID:30529165
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