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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733315
Species: Mus musculus
RGD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il2affects expressionEXP 6480464CTDresveratrol affects the expression of IL2 proteinPMID:14996416
Il2decreases expressionEXP 6480464CTDResveratrol results in decreased expression of IL2 mRNA; Resveratrol results in decreased expression of IL2 proteinPMID:16256029 PMID:17872969 PMID:22962611 PMID:24073240
Il2increases expressionEXP 6480464CTDresveratrol results in increased expression of IL2 proteinPMID:20730501
Il2decreases expressionISOIL2 (Homo sapiens)6480464CTDresveratrol results in decreased expression of IL2 mRNAPMID:22673012
Il2multiple interactionsISOIL2 (Homo sapiens)6480464CTDresveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]PMID:16154495
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