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GENE - TERM ANNOTATION REPORT

RGD ID: 733199
Species: Mus musculus
RGD Object: Gene
Symbol: Top1
Name: topoisomerase (DNA) I
Acc ID: GO:0003917
Term: DNA topoisomerase type I (single strand cut, ATP-independent) activity
Definition: Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
Definition Source(s): PMID:8811192
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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