GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TRPV1 | affects import | EXP | | 6480464 | CTD | TRPV1 protein affects the import of Calcium | PMID:17508023 | TRPV1 | multiple interactions | EXP | | 6480464 | CTD | 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Protons promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [arachidonyl dopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabichromene results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabidivarin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased import of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; iodoresiniferatoxin inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; Ruthenium Red inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 promotes the reaction [Capsaicin results in increased uptake of Calcium] | PMID:11606325 PMID:12569099 PMID:12886029 PMID:15615864 PMID:16597917 PMID:16793902 PMID:17332266 PMID:17442041 PMID:18230619 PMID:19602228 PMID:28790335 PMID:31096838 | TRPV1 | increases import | ISO | Trpv1 (Rattus norvegicus) | 6480464 | CTD | TRPV1 protein results in increased import of Calcium | PMID:18331834 | TRPV1 | multiple interactions | ISO | Trpv1 (Mus musculus) | 6480464 | CTD | Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased transport of Calcium] | PMID:17881535 PMID:18230619 PMID:18249134 | TRPV1 | multiple interactions | ISO | Trpv1 (Rattus norvegicus) | 6480464 | CTD | 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [arachidonyl dopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; [Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium; Amitriptyline inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Butyrates promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Cadmium inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Calcium affects the reaction [mustard oil inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; capsazepine inhibits the reaction [[Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; capsazepine inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Cobalt inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Copper inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Indomethacin inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Lidocaine promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Masoprocol inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; Nickel inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Serotonin promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium] | PMID:12886029 PMID:15471852 PMID:15615864 PMID:16901936 PMID:17590514 PMID:18172555 PMID:19847360 PMID:21453681 PMID:23264033 | | ||||||||||||||||||||||
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