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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733179
Species: Homo sapiens
RGD Object: Gene
Symbol: CCNB1
Name: cyclin B1
Acc ID: CHEBI:35455
Term: 1-naphthyl isothiocyanate
Definition: An isothiocyanate that has formula C11H7NS.
Chemical ID: MESH:D015058
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCNB1increases expressionISOCcnb1 (Rattus norvegicus)6480464CTD1-Naphthylisothiocyanate results in increased expression of CCNB1 mRNAPMID:30723492
CCNB1increases expressionISOCcnb1 (Mus musculus)6480464CTD1-Naphthylisothiocyanate results in increased expression of CCNB1 mRNA; 1-Naphthylisothiocyanate results in increased expression of CCNB1 proteinPMID:29660435
CCNB1multiple interactionsISOCcnb1 (Mus musculus)6480464CTDobeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [yangonin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 mRNA]]; pregna-4,17-diene-3,16-dione inhibits the reaction [yangonin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 protein]]; yangonin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 mRNA]; yangonin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 protein]PMID:29660435
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