GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Plau | affects expression | ISO | PLAU (Homo sapiens) | 6480464 | CTD | Decitabine affects the expression of PLAU mRNA | PMID:23300844 | Plau | increases expression | ISO | PLAU (Homo sapiens) | 6480464 | CTD | Decitabine results in increased expression of PLAU mRNA | PMID:16367923 PMID:18025290 | Plau | multiple interactions | ISO | PLAU (Homo sapiens) | 6480464 | CTD | [Decitabine affects the methylation of PLAU promoter] which affects the expression of PLAU mRNA; Decitabine inhibits the reaction [sodium arsenite results in increased expression of PLAU mRNA]; Decitabine inhibits the reaction [sodium arsenite results in increased expression of PLAU protein] | PMID:18320071 PMID:21167264 | |
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