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GENE - TERM ANNOTATION REPORT

RGD ID: 733095
Species: Homo sapiens
RGD Object: Gene
Symbol: HMBS
Name: hydroxymethylbilane synthase
Acc ID: GO:0006779
Term: porphyrin-containing compound biosynthetic process
Definition: The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
Definition Source(s): GOC:jl, ISBN:0198506732, Wikipedia:Porphyrin#Natural_formation
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMBS ISOHmbs (Rattus norvegicus)9068941RGDUrophorphyrin

PMID:6732900 REF_RGD_ID:25394584
HMBS ISOHmbs (Rattus norvegicus)9068941RGDUrophorphyrin I

PMID:3963818 PMID:6694518 PMID:994723 REF_RGD_ID:25330343 REF_RGD_ID:25440497 REF_RGD_ID:4144803
HMBS ISOHmbs (Rattus norvegicus)9068941RGDUroporphyrin

PMID:1781034 REF_RGD_ID:25440495
HMBS ISOHmbs (Rattus norvegicus)9068941RGDUroporphyrin I

PMID:11202056 PMID:3179323 PMID:6893114 PMID:971328 REF_RGD_ID:2301707 REF_RGD_ID:25394583 REF_RGD_ID:26923963 REF_RGD_ID:4144783
HMBS ISOHmbs (Rattus norvegicus)9068941RGDuroporphyrin I

PMID:11786116 REF_RGD_ID:26923962
HMBS ISOHmbs (Rattus norvegicus)9068941RGDUroporphyrinogen

PMID:3702597 REF_RGD_ID:4144820
HMBSinvolved_inIEAARBA:ARBA00027896150520179UniProt GO_REF:0000117
HMBSinvolved_inIEAUniProtKB-KW:KW-0627150520179UniProt GO_REF:0000043
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