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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733073
Species: Mus musculus
RGD Object: Gene
Symbol: Slc40a1
Name: solute carrier family 40 (iron-regulated transporter), member 1
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc40a1affects expressionEXP 6480464CTDCopper affects the expression of SLC40A1 mRNA; Copper affects the expression of SLC40A1 proteinPMID:16614410
Slc40a1increases expressionEXP 6480464CTDCopper deficiency results in increased expression of SLC40A1 mRNA; Copper deficiency results in increased expression of SLC40A1 protein; Copper results in increased expression of SLC40A1 mRNA; Copper results in increased expression of SLC40A1 proteinPMID:20016736 PMID:23555700
Slc40a1multiple interactionsEXP 6480464CTDEPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of SLC40A1 mRNA]PMID:23555700
Slc40a1decreases expressionISOSlc40a1 (Rattus norvegicus)6480464CTDCopper deficiency results in decreased expression of SLC40A1 proteinPMID:18505688
Slc40a1decreases expressionISOSLC40A1 (Homo sapiens)6480464CTDCopper deficiency results in decreased expression of SLC40A1 mRNAPMID:18505688
Slc40a1increases expressionISOSlc40a1 (Rattus norvegicus)6480464CTDCopper deficiency results in increased expression of SLC40A1 mRNA; Copper deficiency results in increased expression of SLC40A1 proteinPMID:20164366 PMID:21355016
Slc40a1increases expressionISOSLC40A1 (Homo sapiens)6480464CTDCopper results in increased expression of SLC40A1 mRNA; Copper results in increased expression of SLC40A1 proteinPMID:12220667
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