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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733072
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC40A1
Name: solute carrier family 40 member 1
Acc ID: CHEBI:18291
Term: manganese atom
Definition: A manganese group element atom that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC40A1increases exportEXP 6480464CTDSLC40A1 protein results in increased export of ManganesePMID:22178646
SLC40A1multiple interactionsEXP 6480464CTDCobalt inhibits the reaction [SLC40A1 protein results in increased export of Manganese]; Iron inhibits the reaction [SLC40A1 protein results in increased export of Manganese]; Nickel inhibits the reaction [SLC40A1 protein results in increased export of Manganese]PMID:22178646
SLC40A1decreases expressionISOSlc40a1 (Mus musculus)6480464CTDManganese results in decreased expression of SLC40A1 mRNAPMID:29020610
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