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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733057
Species: Mus musculus
RGD Object: Gene
Symbol: Cxcr3
Name: C-X-C motif chemokine receptor 3
Acc ID: CHEBI:29320
Term: calcium(0)
Definition: An elemental calcium that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcr3affects abundanceISOCXCR3 (Homo sapiens)6480464CTDCXCR3 protein affects the abundance of CalciumPMID:12055238
Cxcr3multiple interactionsISOCXCR3 (Homo sapiens)6480464CTD[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of CalciumPMID:12517959 PMID:25833952
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