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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733019
Species: Homo sapiens
RGD Object: Gene
Symbol: PRDX2
Name: peroxiredoxin 2
Acc ID: CHEBI:74077
Term: S-allylcysteine
Definition: An S-hydrocarbyl-L-cysteine that is L-cysteine in which the hydrogen attached to the sulphur is replaced by a prop-2-enyl group. It commonly occurs in garlic and has been found to exhibit antineoplastic activity.
Chemical ID: MESH:C065299
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7354776480464CTD[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of PRDX2 protein], [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]], S-allylcysteine inhibits the reaction [lead acetate affects the localization of PRDX2 protein], S-allylcysteine inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]]

PMID:22033380
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.