GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dusp1 | affects response to substance | EXP | | 6480464 | CTD | DUSP1 protein affects the susceptibility to Resveratrol | PMID:30844440 | Dusp1 | multiple interactions | EXP | | 6480464 | CTD | DUSP1 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; DUSP1 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; DUSP1 protein affects the reaction [Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; Resveratrol inhibits the reaction [titanium dioxide results in increased expression of DUSP1 mRNA] | PMID:30844440 PMID:31298478 | Dusp1 | decreases expression | ISO | Dusp1 (Rattus norvegicus) | 6480464 | CTD | resveratrol results in decreased expression of DUSP1 mRNA | PMID:19228061 | Dusp1 | multiple interactions | ISO | DUSP1 (Homo sapiens) | 6480464 | CTD | [Coumestrol co-treated with resveratrol] results in decreased expression of DUSP1 mRNA; DUSP1 protein inhibits the reaction [resveratrol results in increased activity of EGR1 protein] | PMID:19167446 PMID:25645941 | |
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