GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdkn1a | increases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | temsirolimus results in increased expression of CDKN1A mRNA | PMID:19764996 | Cdkn1a | multiple interactions | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | [S 1 (combination) co-treated with temsirolimus] results in increased expression of CDKN1A protein; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CDKN1A mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA] | PMID:19764996 | | ||||||||||||||||||||||
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