GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdkn1a | increases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | romidepsin results in increased expression of CDKN1A mRNA; romidepsin results in increased expression of CDKN1A promoter; romidepsin results in increased expression of CDKN1A protein | PMID:15014036 PMID:15849726 PMID:16223781 PMID:17230511 PMID:20404564 PMID:34665271 | Cdkn1a | multiple interactions | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A promoter]; alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]; Aspirin promotes the reaction [romidepsin results in increased expression of CDKN1A protein]; calphostin C inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]; Phorbol 12,13-Dibutyrate inhibits the reaction [alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]]; PTGS1 mutant form inhibits the reaction [Aspirin promotes the reaction [romidepsin results in increased expression of CDKN1A protein]]; quizartinib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]; romidepsin promotes the reaction [Tretinoin results in increased expression of CDKN1A mRNA] | PMID:15014036 PMID:16223781 PMID:20404564 PMID:34665271 | | ||||||||||||||||||||||
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