GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AKT1 | multiple interactions | EXP | | 6480464 | CTD | [[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein; Acrolein results in increased expression of and results in increased phosphorylation of AKT1 protein; resorcinol inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein] | PMID:19596284 PMID:26262998 | AKT1 | multiple interactions | ISO | Akt1 (Rattus norvegicus) | 6480464 | CTD | [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of AKT1 protein | PMID:24847785 | AKT1 | multiple interactions | ISO | Akt1 (Mus musculus) | 6480464 | CTD | Acrolein inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein] | PMID:24812010 | | ||||||||||||||||||||||
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