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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732865
Species: Homo sapiens
RGD Object: Gene
Symbol: PRKAA1
Name: protein kinase AMP-activated catalytic subunit alpha 1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRKAA1decreases expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of PRKAA1 proteinPMID:31675489
PRKAA1increases expressionISOPrkaa1 (Rattus norvegicus)6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of PRKAA1 mRNAPMID:27291303
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