GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PRKAA1 | multiple interactions | EXP | | 6480464 | CTD | 6,8-diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein]; [Resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein]; Apigenin inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein]; Glucose inhibits the reaction [SGA 360 results in increased phosphorylation of PRKAA1 protein]; Glucose results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein; Metformin inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein]; PRKAA1 protein affects the reaction [Metformin inhibits the reaction [Glucose deficiency results in increased chemical synthesis of Reactive Oxygen Species]]; PRKAA1 protein affects the reaction [Ribonucleosides inhibits the reaction [Glucose deficiency results in increased chemical synthesis of Reactive Oxygen Species]]; PRKAA1 protein affects the reaction [Rosiglitazone inhibits the reaction [Glucose affects the localization of NCF1 protein]]; PRKAA1 protein affects the reaction [Rosiglitazone inhibits the reaction [Glucose affects the localization of RAC1 protein]]; PRKAA1 protein affects the reaction [Rosiglitazone inhibits the reaction [Glucose results in increased abundance of Reactive Oxygen Species]]; Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein] | PMID:16380484 PMID:16873680 PMID:17916771 PMID:18482975 PMID:31225620 | PRKAA1 | multiple interactions | ISO | Prkaa1 (Mus musculus) | 6480464 | CTD | [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in increased abundance of Glucose-6-Phosphate; [PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]; Glucose results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein; PRKAA1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of SIRT1 protein]] | PMID:19052259 PMID:23090186 PMID:31974165 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |