GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il12b | increases expression | EXP | | 6480464 | CTD | Poly I-C results in increased expression of IL12B mRNA; Poly I-C results in increased expression of IL12B protein | PMID:19426678 PMID:19500611 | Il12b | multiple interactions | EXP | | 6480464 | CTD | Ethanol inhibits the reaction [Poly I-C results in increased expression of IL12B protein]; Luteolin inhibits the reaction [Poly I-C results in increased expression of IL12B mRNA] | PMID:19426678 PMID:19500611 | Il12b | increases expression | ISO | IL12B (Homo sapiens) | 6480464 | CTD | Poly I-C results in increased expression of IL12B protein | PMID:16890772 | Il12b | multiple interactions | ISO | IL12B (Homo sapiens) | 6480464 | CTD | [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein; Particulate Matter analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]; Vehicle Emissions analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein] | PMID:16890772 PMID:23266719 | | ||||||||||||||||||||||
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