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GENE - TERM ANNOTATION REPORT

RGD ID: 732809
Species: Homo sapiens
RGD Object: Gene
Symbol: PFKFB1
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Acc ID: GO:0043540
Term: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
Definition: A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis.
Definition Source(s): GOC:jl, GOC:so
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PFKFB1 ISOPfkfb1 (Rattus norvegicus)9068941RGD PMID:7619077 REF_RGD_ID:2302679
PFKFB1part_ofIEAUniProtKB:P07953 or ensembl:ENSRNOP00000035212150520179Ensembl GO_REF:0000107
PFKFB1part_ofIBAPANTHER:PTN002577872 or Pfkfb1 (Rattus norvegicus) or UniProtKB:P16118150520179GO_Central GO_REF:0000033
PFKFB1part_ofIEAPANTHER:PTHR10606:SF15150520179TreeGrafter GO_REF:0000118
PFKFB1part_ofIDA 150520179UniProt PMID:12379646

PMID:12379646
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