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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732779
Species: Mus musculus
RGD Object: Gene
Symbol: Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Acc ID: CHEBI:70773
Term: capsazepine
Definition: A benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist.
Chemical ID: MESH:C071423
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp1r12amultiple interactionsISOPPP1R12A (Homo sapiens)6480464CTDcapsazepine inhibits the reaction [Colforsin results in increased phosphorylation of PPP1R12A protein]PMID:21474433
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