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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732779
Species: Mus musculus
RGD Object: Gene
Symbol: Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp1r12aaffects methylationEXP 6480464CTDOxygen deficiency affects the methylation of PPP1R12A promoterPMID:24205000
Ppp1r12aincreases expressionEXP 6480464CTDOxygen deficiency results in increased expression of PPP1R12A mRNAPMID:24205000
Ppp1r12amultiple interactionsISOPpp1r12a (Rattus norvegicus)6480464CTD15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein]]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein]; Y 27632 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein]PMID:25305180
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