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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732775
Species: Homo sapiens
RGD Object: Gene
Symbol: ALOX5
Name: arachidonate 5-lipoxygenase
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALOX5increases expressionEXP 6480464CTDGlucose results in increased expression of ALOX5 mRNAPMID:31655124
ALOX5multiple interactionsISOAlox5 (Rattus norvegicus)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein; caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; Edaravone inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; SB 203580 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]PMID:18951527
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