GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ABCG8 | decreases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of ABCG8 mRNA | PMID:20106945 PMID:26159488 | ABCG8 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of ABCG8 mRNA | PMID:21632981 | ABCG8 | multiple interactions | EXP | | 6480464 | CTD | [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ABCG8 mRNA | PMID:26159488 | ABCG8 | decreases expression | ISO | Abcg8 (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of ABCG8 mRNA | PMID:21215274 | ABCG8 | decreases expression | ISO | Abcg8 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of ABCG8 mRNA | PMID:28213091 | ABCG8 | increases expression | ISO | Abcg8 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of ABCG8 mRNA | PMID:25975270 | ABCG8 | multiple interactions | ISO | Abcg8 (Mus musculus) | 6480464 | CTD | [NFE2L2 gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ABCG8 mRNA; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate] promotes the reaction [Dietary Fats results in increased expression of ABCG8 mRNA] | PMID:21846477 PMID:23756648 | |
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