Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732764
Species: Homo sapiens
RGD Object: Gene
Symbol: CHRNB4
Name: cholinergic receptor nicotinic beta 4 subunit
Acc ID: CHEBI:9774
Term: tubocurarine
Definition: A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare.
Chemical ID: MESH:D014403
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDTubocurarine inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]]

PMID:16931985
multiple interactionsISORGD:23516480464CTDTubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]], Tubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]], Tubocurarine results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]

PMID:7808438, PMID:9687574
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.