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GENE - TERM ANNOTATION REPORT

RGD ID: 732733
Species: Homo sapiens
RGD Object: Gene
Symbol: GABRG1
Name: gamma-aminobutyric acid type A receptor subunit gamma1
Acc ID: GO:0045202
Term: synapse
Definition: The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
Definition Source(s): GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GABRG1is_active_inIBAFB:FBgn0000038 or FB:FBgn0086778 or MGI:103156 or MGI:106213 or MGI:87885 or MGI:87887 or MGI:87888 or MGI:87889 or MGI:87890 or MGI:87891 or MGI:87892 or MGI:87893 or MGI:87894 or MGI:87895 or MGI:95613 or MGI:95614 or MGI:95615 or MGI:95619 or MGI:95620 or MGI:95621 or MGI:95622 or MGI:95623 or MGI:95624 or MGI:95625 or MGI:95747 or MGI:95748 or MGI:95749 or MGI:95750 or MGI:95751 or PANTHER:PTN000434994 or Chrna3 (Rattus norvegicus) or Chrna4 (Rattus norvegicus) or Chrna7 (Rattus norvegicus) or Chrnb2 (Rattus norvegicus) or Gabra3 (Rattus norvegicus) or Gabrb1 (Rattus norvegicus) or Gabrb2 (Rattus norvegicus) or Gabrb3 (Rattus norvegicus) or Glra1 (Rattus norvegicus) or Htr3a (Rattus norvegicus) or Gabra1 (Rattus norvegicus) or Gabra2 (Rattus norvegicus) or Gabra5 (Rattus norvegicus) or Gabra6 (Rattus norvegicus) or Gabrd (Rattus norvegicus) or Gabrr2 (Rattus norvegicus) or Gabrg2 (Rattus norvegicus) or Chrna10 (Rattus norvegicus) or Glra3 (Rattus norvegicus) or Chrna9 (Rattus norvegicus) or Gabre (Rattus norvegicus) or Chrna6 (Rattus norvegicus) or UniProtKB:G5EDF1 or UniProtKB:P02708 or UniProtKB:P02715 or UniProtKB:P11230 or UniProtKB:P13536 or UniProtKB:P47869 or UniProtKB:Q04844 or UniProtKB:Q07001 or UniProtKB:Q866A2 or WB:WBGene00001133 or WB:WBGene00001373 or WB:WBGene00002974 or WB:WBGene00006765 or WB:WBGene00006774 or WB:WBGene00006784 or WB:WBGene00006797 or WB:WBGene00013746 or ZFIN:ZDB-GENE-030131-3805 or ZFIN:ZDB-GENE-040808-32 or ZFIN:ZDB-GENE-070821-4150520179GO_Central GO_REF:0000033
GABRG1located_inIEAUniProtKB-KW:KW-0770150520179UniProt GO_REF:0000043
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