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GENE - TERM ANNOTATION REPORT

RGD ID: 732674
Species: Homo sapiens
RGD Object: Gene
Symbol: PDE5A
Name: phosphodiesterase 5A
Acc ID: GO:0047555
Term: 3',5'-cyclic-GMP phosphodiesterase activity
Definition: Catalysis of the reaction: 3',5'-cyclic GMP + H2O = GMP + H+.
Definition Source(s): RHEA:16957
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDE5A ISOPde5a (Rattus norvegicus)9068941RGD PMID:15100365 PMID:15623434 REF_RGD_ID:1582531 REF_RGD_ID:1582533
PDE5AenablesIBAFB:FBgn0038237 or FB:FBgn0085370 or FB:FBgn0264815 or MGI:108413 or MGI:1201792 or MGI:1277179 or MGI:2446107 or PANTHER:PTN001682918 or Pde3b (Rattus norvegicus) or Pde5a (Rattus norvegicus) or Pde1a (Rattus norvegicus) or Pde1c (Rattus norvegicus) or UniProtKB:O00408 or UniProtKB:O60658 or UniProtKB:O76074 or UniProtKB:O76083 or UniProtKB:P14099 or UniProtKB:P14100 or UniProtKB:P54750 or UniProtKB:Q01061 or UniProtKB:Q01064 or UniProtKB:Q14123 or UniProtKB:Q14432 or UniProtKB:Q8I5V4 or UniProtKB:Q8I6Z7 or UniProtKB:Q8IKD3 or WB:WBGene00011433 or dictyBase:DDB_G0268634150520179GO_Central GO_REF:0000033
PDE5AenablesIEARHEA:16957150520179RHEA GO_REF:0000116
PDE5AenablesIEAPANTHER:PTHR11347:SF20 or PANTHER:PTHR11347:SF230150520179TreeGrafter GO_REF:0000118
PDE5AenablesIDA 150520179UniProt PMID:14687666

PMID:14687666
PDE5AenablesIEAEC:3.1.4.35150520179UniProt GO_REF:0000003
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