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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732638
Species: Mus musculus
RGD Object: Gene
Symbol: Ppara
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:8633
Term: puerarin
Definition: A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 7 and 4' and a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage.
Chemical ID: MESH:C033607
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pparamultiple interactionsEXP 6480464CTDpuerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of PPARA mRNA]; puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of PPARA protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]PMID:23927877 PMID:31273855
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