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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732608
Species: Mus musculus
RGD Object: Gene
Symbol: Epcam
Name: epithelial cell adhesion molecule
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epcamincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of EPCAM mRNAPMID:17350061
Epcamdecreases expressionISOEPCAM (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of EPCAM mRNAPMID:12634122
Epcamincreases expressionISOEPCAM (Homo sapiens)6480464CTDsodium arsenite results in increased expression of EPCAM mRNA; sodium arsenite results in increased expression of EPCAM proteinPMID:29240254 PMID:29277653
Epcammultiple interactionsISOEPCAM (Homo sapiens)6480464CTDMIR155 mRNA affects the reaction [sodium arsenite results in increased expression of EPCAM mRNA]; MIR155 mRNA affects the reaction [sodium arsenite results in increased expression of EPCAM protein]; MIR191 mRNA promotes the reaction [sodium arsenite results in increased expression of EPCAM mRNA]; QKI protein affects the reaction [MIR155 mRNA affects the reaction [sodium arsenite results in increased expression of EPCAM protein]]; QKI protein inhibits the reaction [sodium arsenite results in increased expression of EPCAM mRNA]PMID:29240254 PMID:29277653
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