GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Col3a1 | affects expression | EXP | | 6480464 | CTD | Carbon Tetrachloride affects the expression of COL3A1 mRNA | PMID:17484886 PMID:31919559 | Col3a1 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of COL3A1 mRNA; Carbon Tetrachloride results in increased expression of COL3A1 protein | PMID:15056808 PMID:18263696 PMID:25827057 PMID:27339419 PMID:27477297 PMID:28286204 PMID:29987408 PMID:30056145 PMID:33069761 PMID:34224798 PMID:35483553 PMID:36555680 PMID:37573684 | Col3a1 | multiple interactions | EXP | | 6480464 | CTD | 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]; alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased secretion of COL3A1 protein]; alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]; Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]; ANXA6 mRNA affects the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]; Carbon Tetrachloride results in increased expression of and results in increased secretion of COL3A1 protein; Colchicine inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased secretion of COL3A1 protein]; Colchicine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]; CXCL14 mRNA promotes the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]; GPR137B-PS mRNA promotes the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]; NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]]; PPIC protein affects the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased secretion of COL3A1 protein]]; tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein] | PMID:25827057 PMID:27477297 PMID:30056145 PMID:33069761 PMID:34224798 PMID:35483553 PMID:37573684 | Col3a1 | affects expression | ISO | Col3a1 (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride affects the expression of COL3A1 mRNA | PMID:16239168 | Col3a1 | increases expression | ISO | Col3a1 (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of COL3A1 mRNA; Carbon Tetrachloride results in increased expression of COL3A1 protein | PMID:12632512 PMID:17157831 PMID:17485851 PMID:18481824 PMID:22683883 PMID:23500774 | Col3a1 | multiple interactions | ISO | Col3a1 (Rattus norvegicus) | 6480464 | CTD | [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid co-treated with Carbon Tetrachloride] results in increased expression of COL3A1 protein; [Carbon Tetrachloride co-treated with Ethanol] results in increased secretion of COL3A1 protein; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]; methyl ferulate inhibits the reaction [[Carbon Tetrachloride co-treated with Ethanol] results in increased secretion of COL3A1 protein]; Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]; Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]; PLAU protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein] | PMID:12512042 PMID:12632512 PMID:17157831 PMID:18481824 PMID:22683883 PMID:23500774 PMID:30543783 | | ||||||||||||||||||||||
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