GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | epigallocatechin gallate results in increased phosphorylation of MAPK1 protein | PMID:35863485 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK1 protein]; epigallocatechin gallate inhibits the reaction [p-Methoxy-N-methylphenethylamine results in increased phosphorylation of MAPK1 protein]; epigallocatechin gallate inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK1 protein] | PMID:20450880 PMID:29402411 PMID:34740634 | Mapk1 | decreases expression | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in decreased expression of MAPK1 protein modified form | PMID:20346928 | Mapk1 | increases activity | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in increased activity of MAPK1 protein | PMID:17931610 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in increased phosphorylation of MAPK1 protein | PMID:19720055 | Mapk1 | multiple interactions | ISO | Mapk1 (Rattus norvegicus) | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK1 protein]; epigallocatechin gallate results in increased phosphorylation of and results in increased activity of MAPK1 protein; MFN2 protein promotes the reaction [epigallocatechin gallate inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK1 protein]] | PMID:15210717 PMID:28478070 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [epigallocatechin gallate results in increased activity of MAPK1 protein]; [epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK1 protein; epigallocatechin gallate affects the reaction [Doxorubicin affects the expression of MAPK1 protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; epigallocatechin gallate inhibits the reaction [HGF protein results in increased phosphorylation of MAPK1 protein]; epigallocatechin gallate inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]; epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]]; epigallocatechin gallate results in increased expression of and results in increased phosphorylation of MAPK1 protein | PMID:16463383 PMID:17931610 PMID:19244381 PMID:19557821 PMID:23954321 PMID:31252129 PMID:35218280 PMID:36162953 | | ||||||||||||||||||||||
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