GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nphs2 | decreases expression | EXP | | 6480464 | CTD | Folic Acid deficiency results in decreased expression of NPHS2 protein | PMID:21647593 PMID:21893018 | Nphs2 | multiple interactions | EXP | | 6480464 | CTD | [Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of NPHS2 mRNA; CYBB mutant form inhibits the reaction [Folic Acid deficiency results in decreased expression of NPHS2 protein]; CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of NPHS2 mRNA] | PMID:20116427 PMID:21647593 | |
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