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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732441
Species: Homo sapiens
RGD Object: Gene
Symbol: TXN
Name: thioredoxin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TXNaffects expressionEXP 6480464CTDbisphenol A affects the expression of TXN mRNAPMID:30903817
TXNdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TXN mRNAPMID:20678512
TXNmultiple interactionsEXP 6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TXN mRNAPMID:28628672
TXNaffects expressionISOTxn1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of TXN mRNAPMID:25181051
TXNdecreases expressionISOTxn1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of TXN1 mRNAPMID:30816183 PMID:32528016 PMID:34947998
TXNdecreases expressionISOTxn1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of TXN1 mRNAPMID:35598803
TXNincreases expressionISOTxn1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of TXN1 proteinPMID:32145629
TXNincreases expressionISOTxn1 (Mus musculus)6480464CTDbisphenol A results in increased expression of TXN1 mRNAPMID:33221593
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