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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732441
Species: Homo sapiens
RGD Object: Gene
Symbol: TXN
Name: thioredoxin
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TXNaffects metabolic processingEXP 6480464CTDAcrolein affects the metabolism of TXN proteinPMID:17982132
TXNdecreases activityEXP 6480464CTDAcrolein results in decreased activity of TXN proteinPMID:15388247 PMID:17982132
TXNincreases oxidationEXP 6480464CTDAcrolein results in increased oxidation of TXN proteinPMID:18023956 PMID:19135121
TXNmultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Acrolein results in increased oxidation of TXN protein]PMID:18023956
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