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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732375
Species: Mus musculus
RGD Object: Gene
Symbol: Vip
Name: vasoactive intestinal polypeptide
Acc ID: CHEBI:41922
Term: diethylstilbestrol
Definition: An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.
Chemical ID: MESH:D004054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vipincreases expressionISOVip (Rattus norvegicus)6480464CTDDiethylstilbestrol results in increased expression of VIP mRNA; Diethylstilbestrol results in increased expression of VIP proteinPMID:12960047 PMID:15677882 PMID:17005392
Vipmultiple interactionsISOVip (Rattus norvegicus)6480464CTD[Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP mRNA]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]; vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)- promotes the reaction [Diethylstilbestrol results in increased expression of VIP mRNA]PMID:15677882
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