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GENE - TERM ANNOTATION REPORT

RGD ID: 732244
Species: Homo sapiens
RGD Object: Gene
Symbol: DYNLT1
Name: dynein light chain Tctex-type 1
Acc ID: GO:0005868
Term: cytoplasmic dynein complex
Definition: Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
Definition Source(s): GOC:cilia, GOC:hla, GOC:krc, GOC:mah, PMID:12600311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DYNLT1part_ofIBAMGI:98642 or PANTHER:PTN000478852 or Dynlt3 (Rattus norvegicus) or UniProtKB:P51808 or UniProtKB:P63171 or UniProtKB:P63172 or UniProtKB:Q8WW35150520179GO_Central GO_REF:0000033
DYNLT1part_ofIDA 150520179GO_Central PMID:25205765

PMID:25205765
DYNLT1part_ofISSUniProtKB:P63171 or UniProtKB:Q5XI90150520179UniProt GO_REF:0000024
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