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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732227
Species: Homo sapiens
RGD Object: Gene
Symbol: NR3C1
Name: nuclear receptor subfamily 3 group C member 1
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR3C1decreases expressionEXP 6480464CTDAcetylcysteine results in decreased expression of NR3C1 mRNAPMID:16084531
NR3C1multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [anacetrapib results in increased expression of NR3C1 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of NR3C1 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of NR3C1 mRNA]PMID:25617244
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