GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GSR | increases expression | EXP | | 6480464 | CTD | Cadmium results in increased expression of GSR protein | PMID:18061332 | GSR | affects activity | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | Cadmium affects the activity of GSR protein | PMID:16865233 | GSR | decreases activity | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | Cadmium results in decreased activity of GSR protein | PMID:16962696 PMID:17698948 PMID:22127830 PMID:23543441 PMID:24952260 PMID:29975440 PMID:37342552 | GSR | decreases activity | ISO | Gsr (Mus musculus) | 6480464 | CTD | Cadmium results in decreased activity of GSR protein | PMID:17262218 | GSR | decreases expression | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | Cadmium results in decreased expression of GSR; Cadmium results in decreased expression of GSR protein | PMID:17125799 PMID:19615871 | GSR | increases activity | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | Cadmium results in increased activity of GSR protein | PMID:14535831 | GSR | multiple interactions | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | [Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of GSR protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of GSR protein; astaxanthine inhibits the reaction [Cadmium results in decreased activity of GSR protein]; diallyl tetrasulfide inhibits the reaction [Cadmium results in decreased activity of GSR protein]; diallyl tetrasulfide inhibits the reaction [Cadmium results in decreased expression of GSR]; galangin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of GSR protein]; pinostrobin inhibits the reaction [Cadmium results in decreased activity of GSR protein]; Quercetin inhibits the reaction [Cadmium results in decreased activity of GSR protein]; Quercetin inhibits the reaction [Cadmium results in decreased expression of GSR protein]; Vitamin E inhibits the reaction [Cadmium results in increased activity of GSR protein] | PMID:14535831 PMID:16962696 PMID:17125799 PMID:17176674 PMID:17698948 PMID:19615871 PMID:23543441 PMID:24952260 PMID:29975440 PMID:35384154 PMID:37342552 | GSR | multiple interactions | ISO | Gsr (Mus musculus) | 6480464 | CTD | Plant Preparations inhibits the reaction [Cadmium results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Cadmium results in decreased activity of GSR protein] | PMID:17262218 | | ||||||||||||||||||||||
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