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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732220
Species: Mus musculus
RGD Object: Gene
Symbol: Abcg5
Name: ATP binding cassette subfamily G member 5
Acc ID: CHEBI:79997
Term: GW 4064
Definition: A stilbenoid that has formula C28H22Cl3NO4.
Chemical ID: MESH:C412815
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg5increases expressionEXP 6480464CTDGW 4064 results in increased expression of ABCG5 mRNAPMID:22918042 PMID:30996006
Abcg5multiple interactionsEXP 6480464CTDFGF15 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA]PMID:22918042 PMID:30996006
Abcg5increases expressionISOABCG5 (Homo sapiens)6480464CTDGW 4064 results in increased expression of ABCG5 mRNAPMID:34767876
Abcg5multiple interactionsISOABCG5 (Homo sapiens)6480464CTDClavulanic Acid inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA]; GW 4064 inhibits the reaction [Clavulanic Acid results in decreased expression of ABCG5 mRNA]; GW 4064 inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased expression of ABCG5 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA]PMID:34767876
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